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While Phenergan contains Promethazine which is Antihistamine and also act ant vomiting agent.. Sedation is the main side effect. It inhibits the action of serotonin, a chemical messenger that can trigger nausea and vomiting. The reduction in anxiety was similar (ondansetron -13 mm, promethazine -14 mm; difference -1 mm; 95% CI = -10 to 10 mm) 4. It's available in different forms that you don't have to swallow in case you can't keep anything down. Prescribed for Nausea/Vomiting, Nausea/Vomiting - Chemotherapy Induced more Prescription only Phenergan may be used to relieve allergy symptoms, nausea, or as a sleeping aid. Zofran (ondansetron) works well to prevent nausea and vomiting. 05) Regarding your concern I want to share with you that,Zofran contains , Ondansetron is an antiemetic (anti-nausea medicine). Phenergan (Promethazine) is used to treat and prevent nausea and vomiting from surgery, motion sickness, or pregnancy. For intractable nausea, Marinol is also an option What is the best medicine for nausea/vomitting -- Zofran, Reglan or Phenergan? Evidence shows that the outcome at 30 minutes after administration the outcome between zofran and phenergan are equal for relief of nausea. Zofran has safer side effect profile Ondansetron may be used for the prevention or treatment of nausea and vomiting but it may cause constipation or a headache. I''m not exactly sure how Reglan works. Conclusion The main conclusion of the above discussion is that Zofran and Phenergan belong to different drug groups, but they are used to treat nausea and vomiting. Comparing Phenergan vs Zofran Phenergan (promethazine) Zofran (ondansetron) Prescription only Phenergan may be used to relieve allergy symptoms, nausea, or as a sleeping aid. Zofran is a class b drug, safe during pregnancy, phenergan is a class c drug, the effects are unknown. When I had appendicitis and was vomiting every couple of hours and anytime I tried to drink anything, I was grateful for Zofran. There were more side-effects seen in the promethazine-treated when compared to the group with ondansetron treatment (P < 0. Phenergan makes me very tired and out of it, but from what I read Zofran is mostly just for cancer/chemo patients. FWIW, she has cyclic vomiting syndrome with migraines from dysautonomia. Brand names for promethazine include Phenergan, Phenadoz, and Promethegan. I would personally never take phenergan during pregnancy, I would rather deal with the nausea than take the risk. Sedation is the main side effect Zofran does not show a serious side effect; on the other hand, Phenergan shows serious side effects. Heidi Fowler answered Psychiatry 26 years experience Drink it strong: Ginger can reduce nausea & upset stomach Jun 15, 2014 at 11:50 AM. Zofran is really great for severe nausea and vomiting — chemotherapy, for instance. Zofran (ondansetron) Prescription only Phenergan (Promethazine) Prescription only Helps prevent nausea and vomiting. Ondansetron and promethazine reduced nausea similarly (ondansetron -34 mm, promethazine -36 mm; difference -2 mm; 95% CI = -13 to 8 mm). Ondansetron may be used for the prevention or treatment of nausea and vomiting but it may cause constipation or a headache. We use Zofran, Phenergan, and low dose Ativan for nausea. Brand names for ondansetron include Zofran, Zofran ODT, and Zuplenz. Ondansetron and promethazine are used to prevent nausea and vomiting. But you can actually take 4-8mg of zofran every 4-8 hours Plus, phenergan is definitely sedating. Obviously Zofran and Phenergan work in completely different ways. When should you not take Zofran? The reduction in anxiety was similar (ondansetron -13 mm, promethazine -14 mm; difference -1 mm; 95% CI = -10 to 10 mm) Nausea was reduced more significantly in the ondansetron-treated group (P < 0. No significant differences were seen in the blood pressures between groups (P > 0. Sedation is the main side effect Baseline nausea, anxiety, and sedation scores were similar. I have nausea/vomitting almost immediately after eating. 6 / 5 average rating with 366 reviews forZofran. For prophylactic administration zofran has better numbers. Prescribed for Light Sedation, Allergic Reactions, Allergic Rhinitis, Anaphylaxis more Prescription only. The older drug, promethazine, has antihistamine and sedating properties Regarding your concern I want to share with you that,Zofran contains , Ondansetron is an antiemetic (anti-nausea medicine). 4 / 5 average rating with 38 reviews forPhenergan Helps prevent nausea and vomiting. One thing to keep in mind, Zofran can prolong the QT interval, so when was your patient's last EKG? Promethazine is also used as an antihistamine and sedative. 6 / 5 average rating with 366 reviews forZofran Upsides Available in generic Any nausea med rec to take to my gi? Zofran, phernegan, reglan (metoclopramide) & their relations=anaphylaxis. Baseline nausea, anxiety, and sedation scores were similar.

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